Jerry A. Krishnan, MD, PhD; Richard A. Mularski, MD, MSHS, MCR. JAMA. 2010;303(23):2409-2410.
Comparative effectiveness research (CER) has been defined by a report by the Federal Coordinating Council for Comparative Effectiveness as "the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat, and monitor health conditions in ‘real world’ settings.
The purpose of this research is to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, and other decision makers, responding to their expressed needs about which interventions are most effective for which patients under specific circumstances."1
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