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2011 Jan 6 - Lancet Comment: Vitamin D nutrient to treat TB begs the prevention question

2011 Jan 6 - Lancet Comment: Vitamin D nutrient to treat TB begs the prevention question

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The Lancet, Early Online Publication, 6 January 2011

Reinhold Vieth a bIn The Lancet , Adrian Martineau and colleagues 1 report a randomised multicentre trial of vitamin D 3 (colecalciferol) as adjunctive therapy for active tuberculosis, 1 This study, and five other ongoing trials, 2—7 were all designed to show faster recovery from active infection with Mycobacterium tuberculosis .

Martineau and colleagues showed that the addition of vitamin D 3 shortened the time to sputum clearance by 1 week, from 43·5 to 36·0 days, but the decrease did not reach conventional statistical signi ...

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