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2011 Dec 12 - β-agonists for ARDS: the dark side of adrenergic stimulation?

2011 Dec 12 - β-agonists for ARDS: the dark side of adrenergic stimulation?

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B Taylor Thompson. The Lancet, Early Online Publication, 12 December 2011doi:10.1016/S0140-6736(11)61845
 
In The Lancet , Fang Gao Smith and the BALTI-2 study investigators 1 report the findings of their phase-3 randomised trial of intravenous salbutamol for acute respiratory distress syndrome (ARDS). The trial, based on reliable preclinical evidence and an encouraging phase-2 trial, was stopped early because of safety concerns.

β-agonists had been an appealing therapeutic option for ARDS in view of extensive clinical experience, low cost, and an excellent safety profile when used for patients with obst ...

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Last Updated on Friday, 23 December 2011 19:45  

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