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2011 Apr 13 - Lancet Comment: Isoniazid preventive therapy in HIV infection

2011 Apr 13 - Lancet Comment: Isoniazid preventive therapy in HIV infection

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Lori Elizabeth Dodd a, Robert John Wilkinson b c d. The Lancet, Early Online Publication, 13 April 2011

Tuberculosis remains a formidable health problem, nowhere more so than in southern Africa. In South Africa, 1% of the population develop the disease annually. The factor that drives the continued high incidence is HIV co-infection. In some locations, the risk of tuberculosis in people with HIV infection with advanced immunodeficiency is so high that the question is not if, but when, the disease will occur. 1

In response, WHO promotes a three “I's” strategy to combat the epidemic, in addition to it ...

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