Peter M. Small, M.D., and Madhukar Pai, M.D., Ph.D. N Engl J Med 2010; 363:1070-1071, September 9, 2010
The effective treatment of tuberculosis is a lifesaving intervention. The global scale-up of tuberculosis therapy has averted 6 million deaths over the past 15 years, making it one of the greatest public health interventions of our lifetime.1 Unfortunately, by the time most patients are treated, they have already infected many others.2 This failure to interrupt transmission fuels the global epidemic so that every year there are more new cases of tuberculosis than in the previous year.1
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