NEJM Volume 362:2295-2303 June 17, 2010 Number 24
Cigarette smoking remains a leading cause of preventable disease and premature death in the United States and other countries.
On average, 435,000 people in the United States die prematurely from smoking-related diseases each year; overall, smoking causes 1 in 5 deaths. The chance that a lifelong smoker will die prematurely from a complication of smoking is approximately 50%.1
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