NEJM Volume 362:1644-1646 April 29, 2010 Number 17
To the Editor: Though the use of seasonal trivalent inactivated influenza vaccines is recommended in pregnancy, there are few data on the immunogenicity of current vaccine formulations in pregnant women or on the duration of passive protection in their infants.1 We present antibody data for mothers and infants from a prospective, randomized, controlled trial of influenza vaccine in pregnant women,2 the Mother'sGift project.
In brief, 340 Bangladeshi women in the third trimester of pregnancy were randomly assigned to receive either a current commercial trivalent inactivated influenza vaccine (with these mothers and their infants called vaccinees) or a control (23-valent pneumococcal . . . [Full Text of this Article]
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