Hong Kong Respiratory Medicine

Monica Kraft.  N Engl J Med 2011; 365:1141-1144September 22, 2011

Asthma is a chronic inflammatory disease of the airways manifested by reversible airflow obstruction and airway hyperresponsiveness.1 One of the challenges of treating patients with asthma is the known heterogeneity of the disease and differential responses to standard treatments.24 For example, in a large clinical trial of patients with moderate asthma, one of three patients had asthma that was not well controlled despite the regular use for 1 year of fluticasone, an inhaled glucocorticoid, and salmeterol, a long-acting beta-agonist.3 In another study involving patients with more severe asthma, 40% were unable to gain control of their asthma with the . . .

Weblink here