2013 June 6 - Prone Positioning in Severe Acute Respiratory Distress Syndrome
Claude Guérin, M.D., Ph.D., Jean Reignier, M.D., Ph.D., Jean-Christophe Richard, M.D., Ph.D., Pascal Beuret, M.D., Arnaud Gacouin, M.D., Thierry Boulain, M.D., Emmanuelle Mercier, M.D., Michel Badet, M.D., Alain Mercat, M.D., Ph.D., Olivier Baudin, M.D., Marc Clavel, M.D., Delphine Chatellier, M.D., Samir Jaber, M.D., Ph.D., Sylvène Rosselli, M.D., Jordi Mancebo, M.D., Ph.D., Michel Sirodot, M.D., Gilles Hilbert, M.D., Ph.D., Christian Bengler, M.D., Jack Richecoeur, M.D., Marc Gainnier, M.D., Ph.D., Frédérique Bayle, M.D., Gael Bourdin, M.D., Véronique Leray, M.D., Raphaele Girard, M.D., Loredana Baboi, Ph.D., and Louis Ayzac, M.D. for the PROSEVA Study Group
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N Engl J Med 2013; 368:2159-2168June 6, 2013DOI: 10.1056/NEJMoa1214103 Background Previous trials involving patients with the acute respiratory distress syndrome (ARDS) have failed to show a beneficial effect of prone positioning during mechanical ventilatory support on outcomes. We evaluated the effect of early application of prone positioning on outcomes in patients with severe ARDS. 2013 June 13 - Targeted versus Universal Decolonization to Prevent ICU Infection
Susan S. Huang, M.D., M.P.H., Edward Septimus, M.D., Ken Kleinman, Sc.D., Julia Moody, M.S., Jason Hickok, M.B.A., R.N., Taliser R. Avery, M.S., Julie Lankiewicz, M.P.H., Adrijana Gombosev, B.S., Leah Terpstra, B.A., Fallon Hartford, M.S., Mary K. Hayden, M.D., John A. Jernigan, M.D., Robert A. Weinstein, M.D., Victoria J. Fraser, M.D., Katherine Haffenreffer, B.S., Eric Cui, B.S., Rebecca E. Kaganov, B.A., Karen Lolans, B.S., Jonathan B. Perlin, M.D., Ph.D., and Richard Platt, M.D. for the CDC Prevention Epicenters Program and the AHRQ DECIDE Network and Healthcare-Associated Infections Program
Last Updated on Friday, 14 June 2013 00:01
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N Engl J Med 2013; 368:2255-2265June 13, 2013DOI: 10.1056/NEJMoa1207290 Background Both targeted decolonization and universal decolonization of patients in intensive care units (ICUs) are candidate strategies to prevent health care–associated infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). 2013 June 13 - Racemic Adrenaline and Inhalation Strategies in Acute Bronchiolitis
Håvard Ove Skjerven, M.D., Jon Olav Gjengstø Hunderi, M.D., Sabine Kristin Brügmann-Pieper, M.D., Anne Charlotte Brun, M.D., Hanne Engen, M.D., Leif Eskedal, M.D., Ph.D., Marius Haavaldsen, M.D., Bente Kvenshagen, M.D., Ph.D., Jon Lunde, M.D., Leif Bjarte Rolfsjord, M.D., Christian Siva, M.D., Truls Vikin, M.D., Petter Mowinckel, M.Sc., Kai-Håkon Carlsen, M.D., Ph.D., and Karin C. Lødrup Carlsen, M.D., Ph.D.
Last Updated on Thursday, 13 June 2013 23:48
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N Engl J Med 2013; 368:2286-2293June 13, 2013DOI: 10.1056/NEJMoa1301839 Background Acute bronchiolitis in infants frequently results in hospitalization, but there is no established consensus on inhalation therapy — either the type of medication or the frequency of administration — that may be of value. We aimed to assess the effectiveness of inhaled racemic adrenaline as compared with inhaled saline and the strategy for frequency of inhalation (on demand vs. fixed schedule) in infants hospitalized with acute bronchiolitis. 2013 June 13 - Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection
Hai-Nv Gao, M.D., Hong-Zhou Lu, M.D., Ph.D., Bin Cao, M.D., Bin Du, M.D., Hong Shang, M.D., Jian-He Gan, M.D., Shui-Hua Lu, M.D., Yi-Da Yang, M.D., Qiang Fang, M.D., Yin-Zhong Shen, M.D., Xiu-Ming Xi, M.D., Qin Gu, M.D., Xian-Mei Zhou, M.D., Hong-Ping Qu, M.D., Zheng Yan, M.D., Fang-Ming Li, M.D., Wei Zhao, M.D., Zhan-Cheng Gao, M.D., Guang-Fa Wang, M.D., Ling-Xiang Ruan, M.D., Wei-Hong Wang, M.D., Jun Ye, M.D., Hui-Fang Cao, M.D., Xing-Wang Li, M.D., Wen-Hong Zhang, M.D., Xu-Chen Fang, M.D., Jian He, M.D., Wei-Feng Liang, M.D., Juan Xie, M.D., Mei Zeng, M.D., Xian-Zheng Wu, M.D., Jun Li, M.D., Qi Xia, M.D., Zhao-Chen Jin, M.D., Qi Chen, M.D., Chao Tang, M.D., Zhi-Yong Zhang, M.D., Bao-Min Hou, M.D., Zhi-Xian Feng, M.D., Ji-Fang Sheng, M.D., Nan-Shan Zhong, M.D., and Lan-Juan Li, M.D.
Last Updated on Thursday, 13 June 2013 23:50
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N Engl J Med 2013; 368:2277-2285June 13, 2013DOI: 10.1056/NEJMoa1305584 Background During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged and spread among humans in China. Data were lacking on the clinical characteristics of the infections caused by this virus. |
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